Antidepressants & Mania in Bipolar Disorder: 5-HTTPLR Gene Impacts Risk

Bipolar disorder is a mental illness characterized by extreme mood swings between depression and mania. While antidepressants are commonly prescribed to treat the depressive symptoms, they can also trigger manic episodes in some patients. New research suggests having a certain gene may increase this risk. Key Facts: Antidepressants can cause manic episodes, called treatment emergent …

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TDCS for Depression: At-Home Transcranial Direct Current Stimulation

A new study shows that delivering brain stimulation with mild electric current to the forehead at home could be an effective treatment option for people with depression. Key facts: The study tested at-home transcranial direct current stimulation (tDCS) in 16 people with moderate to severe depression. Participants had 28 sessions of tDCS over 6 weeks, …

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New Tinnitus Treatment with Transcutaneous Trigeminal Electrical Stimulation & Notched Sound Therapy

Tinnitus, a persistent ringing or buzzing in the ears, affects millions of people worldwide. A new study tested a combination therapy of trigeminal nerve stimulation and tailored sound therapy that shows promise for reducing tinnitus symptoms and improving quality of life. Key facts: Tinnitus affects approximately 10% of adults, with 2.4% experiencing severe effects on …

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Deep Brain Stimulation (DBS) for Tardive Dyskinesia Treatment

Tardive dyskinesia is a disorder caused by taking certain psychiatric drugs long-term. It involves uncontrollable body movements that can severely impact a person’s quality of life. Deep brain stimulation is a promising new treatment option for severe, drug-resistant tardive dyskinesia. Key Facts: Tardive dyskinesia causes involuntary, repetitive body movements, often of the face, lips, and …

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ADHD Traits Linked to Blood Biomarker miRNA Levels in Children

Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders, affecting around 5% of children and 2.5% of adults worldwide. The core symptoms are inattention, hyperactivity, and impulsivity that interfere with normal functioning and development. ADHD is associated with difficulties in school, work, and social relationships, as well as increased risk for other mental …

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Brainstem Volume Changes & Depression: Abnormalities in New & Recurrent Episodes

Researchers have discovered that changes in a region deep in the brain called the brainstem may contribute to recurring major depressive disorder (MDD). Key findings include: Patients with first-episode and recurrent depression showed volume decreases in brainstem regions like the pons and midbrain compared to healthy individuals. A region called the superior cerebellar peduncle (SCP) …

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Probiotics for Depression: Prebiotics & Synbiotics May Also Help

Depression affects over 270 million people worldwide. New research is investigating whether manipulating gut bacteria with probiotics, prebiotics or synbiotics can help treat depression symptoms. Key Facts: Probiotics are live microorganisms that provide health benefits when consumed. Prebiotics are food for probiotics. Synbiotics contain both probiotics and prebiotics. A meta-analysis combined results from 13 studies …

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Marijuana & Early-Onset Dementia (Age 34): Case Report Involving Cannabis Abuse

A recent case report describes a 34-year old man who developed a rare form of early onset dementia after two years of heavy marijuana use. While concerning, experts say more research is needed to understand the potential risks of cannabis on the developing brain. Key Facts: The man developed frontotemporal dementia, a disorder causing personality …

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Does Eating Chocolate Cause Depression? Links To Theobromine

Theobromine, an ingredient found in chocolate, may impact mood and depression risk. But the details are complicated. Here’s what the science says so far. Key Facts: A recent study found higher theobromine intake was associated with increased depression risk. However, some experts argue the study had limitations in how it measured depression and theobromine intake. …

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