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TL;DR: A 2026 study in Genes & Diseases found that Il6 deficiency, meaning loss of the gene for interleukin-6, worsened Parkinson’s-like motor and dopamine-system injury in mice. Key Findings Il6 knockout worsened movement: Mice lacking Il6 performed worse aft…
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TL;DR: A 2026 mouse study in Blood found that Thrombosomes, a freeze-dried platelet-derived blood product, reduced bleeding, vessel leak, inflammation, and blood-brain-barrier disruption after traumatic brain injury. Key Findings Thrombosomes were tested after…
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TL;DR: A 2026 medRxiv preprint found that soluble CD27 (sCD27), a T-cell activation marker, was elevated in a subgroup of patients with severe psychiatric disorders and was more common when autoimmune disease or abnormal cerebrospinal fluid (CSF) inflammation…
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TL;DR: A 2026 medRxiv preprint linked higher blood inflammatory markers with diffusion MRI signs of altered white-matter microstructure in 457 dementia-free middle-aged and older adults, especially for a combined cytokine score and orientation dispersion index…
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TL;DR: A 2026 Nature Communications paper found that late-stage amyloid beta plaques in APP23 mice recruited CD8 T cells with a type I interferon program, linking Alzheimer-like amyloid pathology to a more adaptive immune response around plaques. Key Findings…
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TL;DR: A 2026 study in Molecular Neurobiology found that Antrodia cinnamomea, a medicinal fungus extract, worked best when carried on citrate-stabilized silver nanoparticles in cell and rat models of Parkinson’s-like dopamine injury. Key Findings 6-OHDA create…
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TL;DR: A 2026 study in Cell Chemical Biology found that alzheimer’s inflammation may be driven by a specific chemical switch: S-nitrosylation of STING at cysteine 148, which pushed innate immune signaling toward synaptic damage. Key Findings STING carried the…
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Gabapentin Plus Hegu Embedding Improved Post-Herpetic Neuralgia TL;DR: Adding weekly Hegu-point catgut embedding to gabapentin cut post-herpetic neuralgia pain and sleep disruption more sharply, raising response from 80.0% to 92.4%. Key Findings 210 randomized…
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C9orf72 Myeloid Cells Restrained Microbial Inflammation TL;DR: A gut-microbe signal called bacterial glycogen triggered damaging inflammation when C9orf72-deficient immune cells could not restrain it, linking an ALS/FTD gene to gut-brain immune control. Key Fi…
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How Lecanemab Clears Brain Amyloid: The Microglia Key TL;DR: Lecanemab, the first Alzheimer’s antibody to slow cognitive decline, works by activating immune cells called microglia through a specific immune signaling pathway, with the molecule SPP1/osteopontin…
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