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TL;DR: A 2026 preprint in medRxiv from the CORE-VNS study reported that vagus nerve stimulation (VNS), a neuromodulation therapy for drug-resistant epilepsy, produced similar 36-month seizure reductions in people with and without prior intracranial epilepsy su…
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TL;DR: A 2026 study in Journal of Pain Research found that spinal cord stimulation and dorsal root entry zone lesioning reduced pain for selected patients with refractory postherpetic neuralgia, but the evidence came from a 10-patient single-center series. Key…
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TL;DR: A 2026 case-series study in Indian Journal of Psychological Medicine reported rapid pain and symptom improvement after accelerated transcranial direct current stimulation in 4 of 5 patients with treatment-resistant bodily distress disorder. Key Findings…
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TL;DR: A 2026 systematic review in Translational Psychiatry found that depression brain-stimulation studies repeatedly linked treatment response to subcallosal cingulate connectivity, but inconsistent methods still limit its use as a treatment-selection biomar…
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Transcranial Magnetic Stimulation (TMS) is emerging as a revolutionary tool in enhancing cognitive functions, with over sixty studies indicating significant improvements in various tasks. Unlike traditional pharmaceutical approaches, TMS offers a non-invasive…
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A new meta-analysis found that continuous theta burst stimulation (cTBS), a novel form of brain stimulation therapy, does not appear to be more effective than sham (placebo) stimulation for treating symptoms of major depression. Key Facts: cTBS is a type of re…
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Focused ultrasound is emerging as a potentially revolutionary new tool for precisely stimulating the brain without surgery. This novel approach could transform how we diagnose and treat everything from depression and OCD to Alzheimer’s and stroke. Key Facts: F…
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Low intensity focused ultrasound (LIFU) is an exciting new non-invasive brain stimulation technology that allows precise neuromodulation of deep brain structures without surgery. Early research shows LIFU can safely and reversibly modulate targeted areas of th…
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A new study published in Frontiers in Psychiatry provides promising evidence that focused ultrasound stimulation of the prefrontal cortex can alleviate depressive behaviors in mice by suppressing inflammatory responses. Key facts: Researchers stimulated the pr…
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New research demonstrates that repeated focused ultrasound treatments can have antidepressant-like effects in rats. The non-invasive technique was able to improve performance on a common test of depressive behaviors. While not a silver bullet solution, focused…
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