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TL;DR: Brain scans of 48 women with borderline personality disorder showed less gray matter in the insula and parts of the frontal lobe than in 54 women without it. Some of those frontal areas were more strongly in sync with other brain regions, and that synci…
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TL;DR: A 2026 mouse study in Translational Psychiatry reported that six days of adolescent THC exposure reduced Reelin-positive cell density in the female prefrontal cortex and cortical thickness across sexes. Prenatal immune activation did not consistently ma…
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TL;DR: A 2026 study in Brain found that creativity in behavioral variant frontotemporal dementia tracked a rostral prefrontal cortex gradient, meaning the functional separation between default-mode and executive-control networks predicted creative performance.…
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TL;DR: A 2026 study in Signal Transduction and Targeted Therapy built a Parkinson’s visual hallucination mouse model and found that a combined behavior map identified hallucination-like episodes better than any single movement measure. Key Findings Model: Rese…
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TL;DR: A 2026 study in Biological Psychiatry: Global Open Science found that trauma-exposed adolescents, especially those with higher posttraumatic stress symptoms, showed disrupted parent-cued fear extinction across skin-conductance, behavioral-learning, and…
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TL;DR: A 2026 study in Nature Communications found that different brain-connectivity measures predicted different parts of associative learning: functional connectivity predicted acquisition, structural connectivity predicted extinction learning, and effective…
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TL;DR: A 2026 study in The British Journal of Psychiatry found that social anxiety disorder was linked to altered communication inside prefrontal control circuits during a functional MRI emotion-regulation task. Key Findings 102-person fMRI sample: The study a…
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TL;DR: A 2025 systematic review in Translational Psychiatry found that substance use disorder was associated with recurring resting-state functional MRI (rs-fMRI), a scan of spontaneous brain-network communication, abnormalities in reward and self-control circ…
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TL;DR: A 2026 exploratory study in Nature Communications found that a first 25 mg psilocybin dose in 28 psychedelic-naive adults increased electroencephalography (EEG), a scalp recording of brain electrical activity, entropy during the acute session and that e…
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Mediodorsal Thalamus Activity Restored Belief Updating TL;DR: A Nature Neuroscience mouse study linked a schizophrenia-risk Grin2a mutation to weaker mediodorsal thalamus activity, impaired belief updating, and behavioral rescue when researchers reactivated th…
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