EXPLORE THE SCIENCE
TL;DR: A 2026 in vitro study in Molecular and Clinical Oncology found that amitriptyline reduced C6 glioma cell viability and PD-L1 checkpoint expression, but the same drug weakened the cell-killing effect of radiation when combined with temozolomide. Key Find…
Read article
TL;DR: A 2026 randomized feasibility trial in JMIR Mental Health found both a structured AI therapy chatbot and ChatGPT reduced PHQ-9 depression scores versus assessment-only control, but neither AI condition improved anxiety significantly or beat the other. K…
Read article
TL;DR: A 2026 systematic review and meta-analysis in Drug and Alcohol Review estimated high adolescent substance-use exposure in South Africa, with lifetime alcohol use at 35.09%, tobacco at 25.47%, and cannabis at 10.47% across community and school-based stud…
Read article
TL;DR: A 2026 study in Neuropsychopharmacology found that reward uncertainty, measured with functional MRI (fMRI), a brain-scan method, engaged different adolescent brain networks during waiting for a possible reward versus learning the outcome, with anxiety a…
Read article
TL;DR: A 2026 study in Neurology Open Access found that in 793 dementia-free adults, higher vitamin D levels around age 39 were associated with less tau readout on PET brain imaging about 16 years later, while amyloid beta did not show the same relationship. K…
Read article
TL;DR: A 2026 study in Journal of Experimental Psychology: Learning, Memory, and Cognition found that across 12 online experiments, memorable faces helped people remember paired names, but memorable scenes did not give the same boost to paired city names or fi…
Read article
TL;DR: A 2006 study in Perception found that synesthesia was estimated to be 88 times more common than the old 0.05% figure after researchers used non-self-referred sampling and objective consistency tests. Key Findings Older conventional wisdom was about 0.05…
Read article
TL;DR: A 2026 study in Science found that a flattering chatbot did more than sound supportive to users: after even a brief exchange, people were more convinced they were right and less willing to apologize or repair interpersonal conflict. Key Findings 11 lead…
Read article
TL;DR: A 2026 study in JAMA Network Open found that a therapy built to restore reward and positive emotion outperformed a matched negative-affect therapy for adults with depression, anxiety, and severely low positive affect. Key Findings PAT beat the matched t…
Read article
TL;DR: A 2026 study in The British Journal of Psychiatry found that serious mental illness labels shifted often in real-world psychiatric records: 64% of patients with schizophrenia, bipolar disorder, or severe major depression received multiple diagnoses over…
Read article