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TL;DR: A 2026 study in Nature Neuroscience from Baylor College of Medicine showed that boosting Sox9, a transcription factor that regulates aging astrocytes, improved astrocytes’ ability to clear amyloid plaques in Alzheimer’s mouse models and preserved cognit…
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TL;DR: A 2026 study in The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences measured a monocyte-specific DNA methylation clock (MonoDNAmAge) in 440 women with and without HIV, and found that accelerated monocyte epigenetic aging was…
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TL;DR: A 2026 longitudinal study in Appetite following 491 Quebec children found that infants breastfed for at least three to six months showed better inhibitory control — the ability to suppress an automatic response — at age three and a half than infants who…
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Connexin 36 Loss Disrupted Thalamocortical Synchrony TL;DR: Deleting connexin 36 left broad sleep architecture mostly intact but disrupted fast brain electrical rhythms measured by electroencephalography (EEG), along with sensory-response markers often discuss…
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Connectome-seq Turned Synapses Into Barcodes TL;DR: Connectome-seq is a 2026 Nature Methods platform that maps brain wiring by combining engineered synaptic proteins, RNA barcodes, single-nucleus sequencing, and single-synaptosome sequencing. In a mouse pontoc…
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Gabapentin Plus Hegu Embedding Improved Post-Herpetic Neuralgia TL;DR: Adding weekly Hegu-point catgut embedding to gabapentin cut post-herpetic neuralgia pain and sleep disruption more sharply, raising response from 80.0% to 92.4%. Key Findings 210 randomized…
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How Five-Animal Play Matched Probiotics in Prediabetes TL;DR: 4 weeks of Huatuo Five-Animal Play improved glucose control and insulin resistance about as much as bifidobacterium capsules, outperforming low-intensity cycling on several metabolic markers, includ…
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C9orf72 Myeloid Cells Restrained Microbial Inflammation TL;DR: A gut-microbe signal called bacterial glycogen triggered damaging inflammation when C9orf72-deficient immune cells could not restrain it, linking an ALS/FTD gene to gut-brain immune control. Key Fi…
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Brain Age MRI Mapped Stroke Recovery in 501 Patients TL;DR: A Lancet Digital Health ENIGMA study found that larger stroke lesions made the damaged hemisphere look biologically older, while severe motor impairment was linked to younger-appearing contralesional…
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Blood GFAP Started Mirroring the Brain Only After the BBB Leaked TL;DR: Blood biomarkers mostly failed to mirror the brain while the blood-brain barrier stayed intact; once the barrier leaked, glial fibrillary acidic protein (GFAP), an astrocyte injury protein…
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