Researchers have uncovered an important new mechanism that causes inflammation and damage to the brain’s white matter in Alzheimer’s disease. This discovery about how brain cells called microglia die could lead to new Alzheimer’s treatments. Key Facts: The study found that microglia, which are immune cells in the brain, die through a process called “ferroptosis” …
A new large genetics study has discovered new clues into how levels of a protein called apolipoprotein E (ApoE) in the blood may influence a person’s risk of developing Alzheimer’s disease. Key facts: Researchers found 9 new genetic variants that influence ApoE levels in the blood. Some raise levels, while others lower levels. People with …
Prescription opioid painkillers like oxycodone can be very addictive. People who use them for a long time often have trouble stopping, even if the drugs start causing problems. A new study tested a drug that blocks brain signals that keep people wanting opioids. The drug helped rats stop seeking oxycodone and improved their sleep and …
Researchers explored the relationship between body weight and depression symptoms in teens and adults. They found a link between higher body weight and increased depression, especially among teens. Genetic factors appear to play only a small role. Key Facts: Teens who had higher body mass index (BMI) at age 12 were more likely to have …
Schizophrenia is a mental disorder that affects how people think, feel, and behave. It involves problems with hallucinations, delusions, disorganized thinking, lack of motivation, and impaired functioning. Schizophrenia affects about 1% of the population and typically starts in late adolescence or early adulthood. The causes are still poorly understood. In a new study, researchers found …
A new study found that a program to provide more social contact and activities for prisoners in solitary confinement led to improved mental health and behavior. The program was based on a “Resource Team” model developed in Norway. Key Facts: Solitary confinement involves isolating prisoners in cells for 22+ hours per day with limited social …
Researchers developed a new gene editing technique that reduces anxiety in mice. The technique uses CRISPR technology to edit a specific gene in the brain called HTR2A. Editing this gene leads to lower levels of anxiety behaviors in tests with mice. This research demonstrates the potential of using gene editing tools like CRISPR to precisely …
Cigarette smoking and mental health problems often go hand-in-hand. But which one typically comes first? And how much does our genetic makeup contribute to this risky combo? New research examined these questions by analyzing long-term health data on over 300,000 people in the UK. Key Facts: Smoking initiation typically happened in adolescence, before the first …
A new study published in Nature Medicine has identified two biological profiles, based on routine blood tests during COVID-19 hospitalization, that can predict patients’ risk of developing post-COVID brain fog months later. Key Facts: The study analyzed data from over 1,800 COVID-19 patients hospitalized in the UK. It linked certain patterns of blood biomarkers during …
A new neurology study provides compelling evidence that retinal imaging can detect Parkinson’s disease years before diagnosis. Researchers found thinning of two inner retinal layers – the ganglion cell-inner plexiform layer (GCIPL) and inner nuclear layer (INL) – in people who went on to develop Parkinson’s disease up to 7 years later. These findings suggest …
