TL;DR: A 2026 medRxiv preprint found that stroke thrombectomy operators often had a preferred device technique, but that preference did not reliably match the technique with the highest first-pass reperfusion rate. Key Findings Stroke thrombectomy cohort: The single-center analysis included 1,405 acute ischemic stroke patients treated with mechanical thrombectomy from 2019 through 2024. 75% had …
TL;DR: A 2026 preprint posted on medRxiv reported that resting-state electroencephalography (EEG) neural slowing after stroke tracked secondary thalamic degeneration measured on structural MRI, even though the sampled patients did not have direct thalamic lesions. Key Findings 25 stroke patients: Researchers studied adults at least 3 months after unilateral supratentorial stroke and compared their resting-state …
TL;DR: A 2026 randomized trial in Physiotherapy Research International found that adding active 5 Hz repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex to dual-task stroke rehabilitation produced larger gains in Timed Up-and-Go performance, balance confidence, and cognitive screening than sham stimulation plus the same training. Key Findings Small randomized trial: The study …
TL;DR: A 2026 prospective mild-stroke cohort study in Circulation linked basilar artery dolichoectasia and wider cranial arteries to lacunar stroke and cerebral small-vessel disease, while large-artery stenosis did not show the same association. Key Findings 229 mild-stroke patients: The Mild Stroke Study 3 cohort included lacunar and mild nonlacunar ischemic stroke patients followed with MRI …
TL;DR: A 2026 secondary analysis in PLOS One found that low-intensity focused ultrasound and repetitive transcranial magnetic stimulation (rTMS) had similar short-term post-stroke motor endpoint scores, while change-from-baseline Fugl-Meyer gains were larger with focused ultrasound. Key Findings 50-person comparison: The analysis compared 25 subacute stroke patients assigned to LIFU with 25 assigned to rTMS. 10 …
TL;DR: A 2026 study in the International Journal of General Medicine found that rapid ASPECTS scoring on non-contrast CT and CT perfusion core-infarct volume predicted 90-day outcomes similarly in 82 acute ischemic stroke patients treated with endovascular therapy. Key Findings 82 stroke patients: The retrospective single-center study included acute ischemic stroke patients treated with endovascular …
TL;DR: A 2026 preprint in medRxiv from a Dutch comprehensive stroke center found that ischemic stroke patients with a migration background were more likely to arrive outside the treatment time window and less likely to receive endovascular thrombectomy than patients without a migration background. Key Findings 232 first-ever ischemic stroke patients were included: 62 patients, …
TL;DR: A 2026 narrative review in Journal of Central Nervous System Disease found that glucagon-like peptide-1 receptor agonists have promising stroke-prevention and animal-model evidence, but human data do not yet support routine use as an acute ischemic stroke neuroprotective treatment. Key Findings Search through January 2026: The review covered preclinical stroke models, observational studies, randomized …
TL;DR: A 2026 systematic review posted on medRxiv found that transcranial direct current stimulation (tDCS), a weak noninvasive brain-stimulation method, added to cognitive training produced a small short-term cognitive benefit across 27 trials, but the effect faded at follow-up and the evidence certainty was very low. Key Findings 27 controlled studies: The meta-analysis included 1,012 …
TL;DR: A 2026 rat and cell study in Journal of Materials Science: Materials in Medicine reported that an engineered VIN nanosystem shifted microglia toward an anti-inflammatory state and reduced ischemic-stroke infarct measures in MCAO rats. Key Findings CXCR4 increased 1.75-fold: Fe3O4 nanoparticle induction raised CXCR4 expression in bone-marrow mesenchymal stem cell membranes. A151 loading reached …
