TL;DR: A 2026 randomized pilot study in JMIR Formative Research found that one brief yoga session did not significantly change salivary cortisol compared with quiet sitting, but it did raise heart rate during the active movement phase. Key Findings Yoga pilot sample: The pilot randomized 19 adults, with 10 participants assigned to a 24-minute yoga …
TL;DR: A 2026 preprint in medRxiv found that brain-derived p-tau217%, a blood marker designed to isolate central nervous system tau, classified Alzheimer disease pathology better than standard plasma p-tau217 in several Alzheimer cohorts. Key Findings CNS-selective ratio: The proposed marker, brain-derived p-tau217%, estimates the share of circulating tau that is both brain-derived and phosphorylated at …
TL;DR: A 2026 study in PLOS Computational Biology found that people overestimated an opponent’s competitiveness after betrayal, especially when they chose to watch the opponent instead of controlling their own avatar. Key Findings 62-person social task: 62 adults played a 2D prey-pursuit game with a computerized opponent whose hidden friendliness changed over time. Betrayal shifted …
TL;DR: A 2026 mouse study in Nature found that the astrocyte glucocorticoid receptor pathway helped mature visual cortex circuitry and restricted ocular dominance plasticity, linking light exposure, stress-hormone input, and astrocyte-driven circuit closure. Key Findings 70,907 cells profiled: SHARE-seq mapped RNA expression and chromatin accessibility across visual cortex development in normal-reared and dark-reared mice. Five …
TL;DR: A 2026 study in the International Journal of General Medicine found that rapid ASPECTS scoring on non-contrast CT and CT perfusion core-infarct volume predicted 90-day outcomes similarly in 82 acute ischemic stroke patients treated with endovascular therapy. Key Findings 82 stroke patients: The retrospective single-center study included acute ischemic stroke patients treated with endovascular …
TL;DR: A 2026 randomized feasibility trial in Nature Medicine found that gait-synchronized adaptive deep brain stimulation was feasible and safe in 5 people with Parkinson’s disease, with early findings of improved gait symmetry, lower variability, and fewer reported falls than continuous stimulation. Key Findings 5 Parkinson’s patients: The 1-center feasibility trial enrolled people with Parkinson’s …
TL;DR: A 2026 Nature Neuroscience study used cross-species functional MRI (fMRI) connectivity to identify hypoconnectivity and hyperconnectivity autism subtypes linked to different synaptic and immune-related biological pathways. Key Findings 20 mouse models: Autism-relevant mouse models clustered into 11 hypoconnectivity-dominant and 9 hyperconnectivity-dominant fMRI patterns. 1,976 human scans: The human dataset included 940 autistic individuals and …
TL;DR: A 2026 review in Drug Design, Development and Therapy argued that glucagon-like peptide-1 (GLP-1) receptor agonists, drugs that mimic a metabolic hormone involved in glucose control, have credible brain-protection mechanisms, but clinical evidence for neurological disorders remains mixed. Key Findings 15-page review: Li et al. summarized GLP-1 receptor agonist mechanisms and evidence across neurodegenerative, …
TL;DR: A 2026 longitudinal study in Cerebral Cortex linked neighborhood disadvantage in childhood to lower adolescent cortical thickness and surface area, while better educational and health/environmental opportunities tracked greater MRI-estimated cortical thickness and surface area with slower developmental decline. Key Findings 11,639 adolescents: The analysis used ABCD Study neuroimaging data from 11,639 participants with at …
TL;DR: A 2026 preprint in bioRxiv found that Magnetic Resonance Artificial Intelligence Velocimetry (MR-AIV), a physics-informed AI method for estimating brain fluid transport, produced stable velocity and permeability maps across several modeling stress tests. Key Findings Brain-fluid target: MR-AIV estimates three-dimensional velocity, pressure, and permeability fields from dynamic contrast-enhanced MRI. 10-region initialization: A universal, anatomically …
