Math-Music Link Nearly Vanished After Accounting for Intelligence

Math-Music Link Nearly Vanished After Accounting for Intelligence

TL;DR: A 2026 Journal of Intelligence study of 170 adults found that math ability and music ability were only weakly related, and the link was reduced to almost zero after researchers accounted for general intelligence. Key Findings Adult ability groups were tested: The 170-person sample included math specialists, music specialists, and controls who did not …

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Emotional Memory fMRI Separated Arousal From Valence Effects

Emotional Memory fMRI Separated Arousal From Valence Effects

TL;DR: A 2026 Imaging Neuroscience functional MRI (fMRI) study found that emotional pictures were recalled better than neutral pictures, but amygdala and insula activity appeared tied mainly to arousal rather than whether memories were negative or positive. Key Findings Large fMRI sample: The main imaging analysis used 1,006 healthy young adults from a single center. …

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Inaudible Infrasound Increased Stress Hormones and Negative Mood in Controlled Trial

Inaudible Infrasound Increased Stress Hormones and Negative Mood in Controlled Trial

TL;DR: A 2026 Frontiers in Behavioral Neuroscience study reported that inaudible infrasound shifted mood toward unease and raised stress-hormone markers under controlled conditions, offering a physiological explanation for some room-specific fear sensations without supporting supernatural claims. Key Findings Inaudible infrasound shifted mood: Controlled exposure produced measurable mood changes — toward unease, anxiety, and a felt …

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Loneliness-Isolation Mismatch Predicted Cognition Through Chronic Disease

Loneliness-Isolation Mismatch Predicted Cognition Through Chronic Disease

TL;DR: A 2026 MIDUS mediation study in Brain, Behavior, & Immunity – Health found that social asymmetry was associated with greater chronic disease burden, while chronic disease burden mediated links between social asymmetry and episodic memory and executive function, while allostatic load did not. Key Findings Study type: a structural equation modeling study of social …

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Lateral Septal PACAP Signaling Regulated Stress and Anxiety Responses

Lateral Septal PACAP Signaling Regulated Stress and Anxiety Responses

TL;DR: A 2026 rat study in Neuropsychopharmacology found that PACAP/PAC1 signaling in the lateral septum changed forced-swim coping, ACTH stress-hormone release, open-arm exploration, and grooming behavior. Key Findings Stress changed PACAP signals by brain region: Acute swim stress increased PACAP mRNA in the lateral septum, BNST, and basolateral amygdala, while chronic variable mild stress reduced …

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Quantitative MRI Detected White Matter Injury Linked to MoCA Scores

Quantitative MRI Detected White Matter Injury Linked to MoCA Scores

TL;DR: A 2026 medRxiv preprint used quantitative multi-parametric MRI mapping in 245 BeLOVE participants and found that white matter hyperintensities had lower MTsat and R1 plus higher proton density, with nearby normal-appearing white matter also showing microstructural changes linked to MoCA, a brief cognitive screening score. Key Findings 245 MRI participants: The analysis used cerebral …

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Late-Window Stroke IVT Did Not Improve Thrombectomy Outcomes

Late-Window Stroke IVT Did Not Improve Thrombectomy Outcomes

TL;DR: A 2026 medRxiv preprint found that giving intravenous thrombolysis (IVT), a clot-dissolving drug treatment, before endovascular thrombectomy (EVT), a catheter procedure to remove a large brain clot, did not significantly improve 3-month recovery or increase bleeding risk in selected stroke patients treated 6 to 24 hours after symptoms began. Key Findings Registry cohort: The …

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Serum and CSF Metabolites Were Linked to Knee Osteoarthritis Pain

Serum and CSF Metabolites Were Linked to Knee Osteoarthritis Pain

TL;DR: A 2026 cross-sectional metabolomics study in Brain, Behavior, & Immunity – Health found that serum and cerebrospinal fluid (CSF) metabolite signatures differed in knee osteoarthritis and related to pain, fatigue, sleep, and pressure sensitivity, while CSF histamine and 3-hydroxyphenylacetic acid were associated with pain intensity and sleep disturbance. Key Findings Study type: a targeted …

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Parental Severe Mental Illness Linked to Offspring Cognitive Performance

Parental Severe Mental Illness Linked to Offspring Cognitive Performance

TL;DR: A 2026 Psychological Medicine meta-analysis of 109 studies linked parental severe mental illness, especially schizophrenia and bipolar disorder, to lower cognitive performance in offspring across IQ, language, memory, executive function, and general cognition. Key Findings Scale: The review included 109 studies and 1,586,339 participants. Schizophrenia: Offspring of parents with schizophrenia had lower scores across …

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GLP-1 Drugs Suppressed Reward Feeding Through a Central Amygdala Circuit

GLP-1 Drugs Suppressed Reward Feeding Through a Central Amygdala Circuit

TL;DR: A 2026 mouse study in Nature found that small-molecule glucagon-like peptide 1 receptor agonists (GLP-1RAs), obesity and diabetes drugs built around a glucose-linked hormone pathway, suppressed palatable-food intake through central amygdala neurons that lowered nucleus accumbens dopamine. Key Findings Humanized mouse model: Researchers engineered mice so small-molecule GLP-1 receptor agonists could be studied despite …

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