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TL;DR: A 2026 rat study in Brain Structure and Function found that ventral pallidum activity supports juvenile social play, while activating inhibitory nucleus accumbens inputs to the ventral pallidum reduced play behavior in both male and female rats. Key Fin…
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TL;DR: A 2026 study in Journal of Neuroinflammation found that people with multiple sclerosis had altered peripheral immunoglobulin repertoires, and several disease-modifying treatments shifted B-cell repertoire patterns after 6 months. Key Findings 33 MS pati…
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TL;DR: A 2026 preprint in medRxiv from a Dutch comprehensive stroke center found that ischemic stroke patients with a migration background were more likely to arrive outside the treatment time window and less likely to receive endovascular thrombectomy than pa…
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TL;DR: A 2026 mouse study in The Journal of Neuroscience found that the HIV-1 protein gp120 amplified pain signaling through α2δ-1-bound NMDA receptors in spinal excitatory neurons, and blocking that receptor coupling reversed pain-like hypersensitivity. Key F…
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TL;DR: A 2026 study in Open Life Sciences reported that ELAVL1, an RNA-binding protein, protected stressed retinal cells by maintaining WDR36 protein, reducing p53 activation, and limiting calcium overload in cell and acute mouse pressure-injury models. Key Fi…
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TL;DR: A 2026 mouse study in Nature Communications found that early-life high-fat/high-sugar diet exposure left sex-specific adult feeding and hypothalamic changes, and microbiota-targeted interventions partly restored those effects. Key Findings Early-life HF…
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TL;DR: A 2025 study in Neurology used a Kaiser Permanente target-trial emulation and found that starting a statin was not linked to higher or lower Alzheimer disease or related dementia incidence after the first year. The first-year diagnosis increase likely r…
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TL;DR: A reviewed preprint in eLife found that adult vestibular hair-cell kinocilia carry both primary-cilia and motile-cilia features, including motile-cilia gene signatures and spontaneous motion in bullfrog and mouse balance organs. Key Findings 1,522 mouse…
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TL;DR: A 2026 preprint in medRxiv reported that a urine beta-amyloid protein test kit separated mild cognitive impairment or Alzheimer’s disease from healthy controls in a multicenter Chinese sample, while a 51,187-person community screen showed age-related po…
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TL;DR: A 2026 computational study in PLOS One used GEO Alzheimer’s datasets, 130 machine-learning models, and molecular simulations to identify eight candidate genes that may sit in a trichostatin A-related Alzheimer’s disease network. Key Findings 949 predict…
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