TL;DR: In a small Polish trial of 22 children aged 6 to 9 with coordination problems, coordination exercises with and without moves that cross the body’s center line both improved movement planning and two-sided coordination. Final scores were about the same in both groups. Key Findings 22 children finished: Out of 32 who started, split …
TL;DR: In a 40-person stroke rehab trial, people who did video-game balance training with a tight cuff on the weak thigh improved balance, walking and leg strength more over 4 weeks than people doing the same training without the cuff. The trial was small, short and had no fake-cuff comparison. Key Findings 40 stroke patients, …
TL;DR: When 18 healthy adults walked on a treadmill wearing a powered ankle exoskeleton, their stride lengths varied more from step to step, but their lower legs and feet moved more steadily. Their overall walking rhythm did not change. Key Findings More step-to-step variation: Stride-length variability rose from 1.9% to 2.8%. Steadier near the device: …
TL;DR: Six weeks of home “static hold” arm training made untrained young men about 27% stronger and increased how fast they built up force by about 60%. Brain-to-muscle signals changed too, but tests of a proposed brainstem pathway gave mixed results. Key Findings Stronger fast: Maximum elbow-bending force rose about 27% in trained groups. Quicker …
TL;DR: Across 12 small trials, people with Parkinson’s who trained on walking robots scored a bit better on balance and a timed walking test than people who got other therapy. The evidence is low quality, so the true benefit may be smaller. Key Findings 12 randomized trials: Mostly from China and Italy, mostly mild to …
TL;DR: Pooling 20 small trials in Parkinson’s disease, structured exercise improved movement-exam scores, freezing while walking and one balance test compared with usual care. The strongest evidence was for the movement exam, and no one type of exercise stood out. Key Findings 20 trials, 714 people: Tai chi, dance, treadmill, yoga, strength, water exercise and …
TL;DR: Across 27 trials in older adults with mild memory and thinking problems, tai chi and qigong classes lifted overall thinking scores by a moderate amount compared with no exercise. More weekly minutes were not always better, and the dosing patterns still need testing. Key Findings 27 randomized trials, 2,034 people: All aged 60+ with …
TL;DR: A 2026 randomized trial in Journal of the International Society of Sports Nutrition found that 12 weeks of combined interval resistance and aerobic training increased Maresin-1, an inflammation-resolving lipid mediator, in men with obesity, with the largest insulin-resistance improvement when training was paired with 200 mg/day fisetin. Key Findings 44 men completed the trial: …
TL;DR: A 2026 review in International Journal of Molecular Medicine mapped how exercise and fluoxetine overlap in Alzheimer’s disease mechanisms such as mitochondrial quality control, oxidative stress, inflammation, and neuroplasticity, but clinical combination benefits remain unproven. Key Findings Review article, not trial: Wu and Li synthesized mechanistic evidence on exercise and fluoxetine in Alzheimer’s disease …
TL;DR: A 2026 mouse study in Neuron found that exercise activates ventromedial hypothalamic SF1 neurons, and that this brain response is required for normal endurance gains after training. Key Findings VMH SF1 neurons: Exercise increased activity-linked Bdnf expression in steroidogenic factor-1 neurons in the ventromedial hypothalamus. Training plasticity: Repeated exercise increased both intrinsic excitability and …
