TL;DR: A 2026 randomized clinical trial in JAMA Network Open found that one supervised 30 mg/70 kg psilocybin dose plus cognitive behavioral therapy produced 40.5% six-month smoking abstinence versus 10.0% with a nicotine patch plus the same therapy. Key Findings 40.5% vs. 10% prolonged abstinence at 6 months: 17 of 42 psilocybin participants stayed biochemically …
TL;DR: A 2026 study in the International Journal of Transgender Health found that transgender respondents in the 2020 EU LGBTI Survey II reported more discrimination and violence than cisgender lesbian, gay, and bisexual respondents across 30 European countries, with disability and ethnic-minority status linked to larger disparities. Key Findings 138,212 respondents analyzed: the study used …
TL;DR: A 2026 randomized trial in PLOS One found that 5 MIDI-assisted group music therapy sessions during psychiatric hospitalization reduced Depression Anxiety Stress Scale-21 (DASS-21) stress scores more than 1 session, while anxiety, depression, life satisfaction, and immediate emotional-response measures did not clearly differ by session frequency. Key Findings Stress fell further: DASS-21 stress showed …
TL;DR: A 2026 study in Microbiome found that in older adults at metabolic risk, virgin olive oil was linked to better cognitive preservation and richer gut microbiota, while common refined olive oil pointed the other way. Key Findings Metabolic-risk cohort tracked over time: The analysis followed 656 older adults who were 55-75 years old, cognitively …
TL;DR: A 2025 study in Nutrients found that a systematic review of adolescent diet and mental health found the clearest readout for whole dietary patterns, while single nutrients and supplement-style interventions looked less consistent. Key Findings 19 studies reviewed: The review covered six randomized controlled trials and 13 prospective cohort studies. Diet patterns looked clearer: …
TL;DR: A 2026 human microbiome and intervention study in Nature Communications found that coffee drinkers showed distinct gut microbiome composition and lower several microbial metabolites, while caffeinated and decaffeinated coffee shifted stress and mood measures in the intervention phase. Key Findings Study type: a study of habitual coffee intake, caffeinated and decaffeinated coffee, gut microbes, …
TL;DR: A 2026 study in O&G Open found that cannabis exposure 2–7 years after a first pregnancy was not associated with incident hypertension after adjustment in the nuMoM2b Heart Health Study. Key Findings No adjusted hypertension association: Cannabis exposure was not associated with incident hypertension after adjustment (AOR 1.05; 95% CI, 0.63-1.76). 4,079-person analysis: Researchers …
TL;DR: A 2026 systematic review and meta-analysis in Drug and Alcohol Review estimated high adolescent substance-use exposure in South Africa, with lifetime alcohol use at 35.09%, tobacco at 25.47%, and cannabis at 10.47% across community and school-based studies. Key Findings 30 publications were included: Researchers synthesized 202 prevalence estimates from South African adolescent samples. Total …
TL;DR: A 2026 study in Neurology Open Access found that in 793 dementia-free adults, higher vitamin D levels around age 39 were associated with less tau readout on PET brain imaging about 16 years later, while amyloid beta did not show the same relationship. Key Findings 793 dementia-free adults: Participants had vitamin D measured in …
TL;DR: A 2026 preprint birth-cohort study in medRxiv found that 91.1% of children had experienced violence by age 8, while age-8 violence exposure was associated with higher internalizing, externalizing, total problem scores, and disorder odds. Key Findings Evidence map: a South African birth-cohort analysis using violence reports and child mental health assessment. Study group: 974 …
