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TL;DR: A 2026 preprint on medRxiv found that blood tau markers and neurofilament light tracked different parts of amyotrophic lateral sclerosis (ALS), with tau markers linked more to current lower-motor-neuron and muscle-injury features while neurofilament lig…
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TL;DR: A 2026 study published in BMC Medicine used lesion network mapping to identify a somatic-symptom brain network centered on the right insula and putamen, then linked atrophy inside that network to somatic symptom severity across 399 psychiatric patients.…
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TL;DR: A 2026 protocol in JMIR Research Protocols describes EXCEL-PD, a randomized trial testing whether 26 weeks of virtually supervised home endurance and resistance exercise is feasible, safe, and biologically informative for people with Parkinson disease.…
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TL;DR: A 2026 retrospective analysis posted to medRxiv linked diclofenac and naproxen use in the NACC cohort to lower dementia and Alzheimer disease prevalence, while diclofenac use was also associated with slower Montreal Cognitive Assessment (MoCA) cognitive…
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TL;DR: A 2026 protocol posted to medRxiv describes a nationwide Japan survey designed to measure how dementia specialists handle anti-amyloid antibody therapy, biomarker testing, MRI safety monitoring, service capacity, and patient-choice tradeoffs. Key Findin…
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TL;DR: A 2026 mouse study in Nature found that age-related gut microbiome changes impaired vagal gut-brain signaling and hippocampal memory encoding, while several interventions restored memory performance in aged or microbiome-aged mice. Key Findings Aged mic…
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TL;DR: A 2026 study in Nature recorded human hippocampal neurons during propofol anesthesia and found preserved oddball-tone discrimination, short-term plasticity, and language-related semantic coding during surgical loss of consciousness. Key Findings 7 surgi…
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TL;DR: A 2026 study in Open Medicine used network pharmacology, Alzheimer’s disease transcriptomic datasets, machine learning, Mendelian randomization, and molecular docking to link 6PPD-quinone, a tire-wear chemical transformation product, with inflammation,…
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TL;DR: A 2026 cohort study in PLOS One found that higher fasting plasma vitamin C levels were independently associated with larger MRI-measured gray matter and stronger default mode network (DMN) structural connectivity in 2,044 older adults, but the cross-sec…
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TL;DR: A 2026 randomized trial in International Journal of Clinical and Health Psychology found that older adults who knowingly took placebo pills for 3 weeks reported lower stress and performed better on Digit Span than controls. Key Findings Aging trial cont…
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