Health & Wellness

GLP-1 Receptor Agonists Not Ready for Acute Stroke Neuroprotection, Review Finds

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GLP-1 Receptor Agonists Not Ready for Acute Stroke Neuroprotection, Review Finds

TL;DR: A 2026 narrative review in Journal of Central Nervous System Disease found that glucagon-like peptide-1 receptor agonists have promising stroke-prevention and animal-model evidence, but human data do not yet support routine use as an acute ischemic stroke neuroprotective treatment. Key Findings Search through January 2026: The review covered preclinical stroke models, observational studies, randomized …

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Mental Health Apps Split Depression, Anxiety, and Workplace Well-Being Effects

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Mental Health Apps Split Depression, Anxiety, and Workplace Well-Being Effects

TL;DR: A 2026 randomized trial in JMIR Mental Health found that a 4-week executive-function training app reduced depression and anxiety symptoms at 12-week follow-up, while a self-guided CBT app mainly improved workplace well-being. Key Findings Workplace app trial: Participants with mild-to-moderate depression and anxiety symptoms were assigned to waitlist control, NeuroNation executive-function training, or Moodfit …

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Laypeople Named More Alcohol Than Cannabis Intoxication Cues

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Laypeople Named More Alcohol Than Cannabis Intoxication Cues

TL;DR: A 2026 study in Drug and Alcohol Review found that laypeople reported more and better-developed cues for alcohol intoxication than cannabis intoxication, even though most coded cues for both substances were accurate. Key Findings Intoxication-cue sample: The survey sample was 77.7% female, with an average age of 20.5 years, and came from undergraduate psychology …

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Chicory and Green Tea Sleep Supplement Did Not Beat Placebo in Insomnia Pilot

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Chicory and Green Tea Sleep Supplement Did Not Beat Placebo in Insomnia Pilot

TL;DR: A 2026 pilot trial in PLOS One found that a 7-day chicory-and-green-tea herbal supplement did not improve sleep, quality of life, or objective sleep architecture more than placebo in adults with insomnia. Key Findings Small crossover pilot: The crossover pilot enrolled 10 adults aged 50 years or older with insomnia; 9 were women and …

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Head Impact MEG Changes Mapped to Neurochemical Brain Systems

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Head Impact MEG Changes Mapped to Neurochemical Brain Systems

TL;DR: A 2026 preprint in medRxiv found that head-impact-related magnetoencephalography (MEG) changes in high-school football players were strongest in cortical regions matching specific neurotransmitter and gene-expression maps, especially norepinephrine, nicotinic acetylcholine, APOE, and BDNF-related patterns. Key Findings MEG tracked pre-to-post-season brain signaling across 278 timepoints from 91 male high-school football players. Concussion-related cortical slowing aligned …

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Early Psychosis Linked to Work and Education Disruption in SEEearly Cohort

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Early Psychosis Linked to Work and Education Disruption in SEEearly Cohort

TL;DR: A 2026 study in European Archives of Psychiatry and Clinical Neuroscience found that more than half of 184 young adults entering an early-psychosis supported employment and education trial were not in work, school, or training, even though nearly all had finished at least lower- or upper-secondary schooling. Key Findings The SEEearly cohort included 184 …

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Violent Pornography Arousal Linked to Learning, Not Evolution

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Violent Pornography Arousal Linked to Learning, Not Evolution

TL;DR: A 2026 study in Journal of Sex Research found that in 571 German women, arousal to an aggressive written sexual narrative was better explained by sex drive, rape myth acceptance, and prior violent pornography exposure than by evolutionary life-history markers. Key Findings 571 women were quota-sampled: The German sample was selected to reflect age …

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Opioid Use Disorder Drove 30-Year Rise in US Substance Use Burden

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Opioid Use Disorder Drove 30-Year Rise in US Substance Use Burden

TL;DR: A 2026 study in Population Health Metrics used Global Burden of Disease 2019 estimates and found that U.S. substance-use-disorder health loss rose sharply from 1990 to 2019, with opioid use disorders driving the largest increase. Key Findings 19.5 million cases: Estimated U.S. substance use disorder prevalence increased from 12.6 million in 1990 to 19.5 …

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UK Perinatal Lithium Prescribing Was Rare and Often Interrupted

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UK Perinatal Lithium Prescribing Was Rare and Often Interrupted

TL;DR: A 2026 cohort study in The British Journal of Psychiatry found that lithium prescribing around pregnancy was rare in UK primary care records, and most pre-pregnancy lithium users did not stay on treatment through all three trimesters. Key Findings 752,112 pregnancies analyzed: Researchers used UK Clinical Practice Research Datalink GOLD records from 1995 to …

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Depressive Symptoms Accelerated Four Years Before Death in Twin Consortium

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Depressive Symptoms Accelerated Four Years Before Death in Twin Consortium

TL;DR: A 2025 study in Psychological Science found that depressive symptoms accelerated about 4 years before death in a multinational twin consortium, suggesting that late-life mood worsening can partly reflect terminal decline rather than chronological age alone. Key Findings 2,411 older-adult records: Researchers analyzed longitudinal depressive-symptom data from the Interplay of Genes and Environments across …

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