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TL;DR: A 2026 mouse study in Alcohol: Clinical and Experimental Research found that chronic intermittent ethanol plus repeated forced-swim stress left mice drinking more alcohol months later and impaired reversal learning in midlife, alongside locus coeruleus…
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TL;DR: A 2026 open-label study in Communications Medicine found that Bacillus Calmette-Guerin (BCG) immunotherapy changed cerebrospinal-fluid immune-cell responses and Alzheimer-related biomarkers in 23 older adults. Key Findings Small trial context: 2 related…
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TL;DR: A 2026 review in Translational Psychiatry argues for a biologically meaningful inflammatory depression subgroup, with CRP, IL-6, TNF-alpha, glial activation, kynurenine metabolism, and synaptic plasticity linking immune signaling to symptoms and treatme…
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TL;DR: A 2026 Neuron study proposed that developing brain cells can gain positional information partly from lineage, because cells descended from the same progenitor tend to stay near one another as tissue grows. Key Findings Lineage as position signal: The mo…
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TL;DR: A 2026 methodology paper in European Archives of Psychiatry and Clinical Neuroscience describes EMBER-MDD, a research-only multi-omic study designed to find treatment-resistance and esketamine-response biomarkers in about 420 adults with major depressiv…
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TL;DR: A 2026 study in Nature Machine Intelligence reported that a textile soft hand exoskeleton with thumb control and surface electromyography (sEMG) intent detection restored practical grasping in one person with severe ALS-related hand paralysis and helped…
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TL;DR: A 2026 cohort study in PLOS One found that higher fasting plasma vitamin C levels were independently associated with larger MRI-measured gray matter and stronger default mode network (DMN) structural connectivity in 2,044 older adults, but the cross-sec…
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TL;DR: A 2026 feasibility study in the Journal of Activity, Sedentary and Sleep Behaviors found that pregnant participants could use a research-grade accelerometer plus text-message sleep diaries across much of pregnancy, although third-trimester wear declined…
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TL;DR: A 2026 study in Brain, Behavior, & Immunity – Health linked composite inflammatory biomarkers during pregnancy and postpartum with postpartum anxiety symptoms, but the strongest associations ran in the unexpected direction of lower anxiety risk at highe…
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TL;DR: A 2026 review in Journal of Pain Research argues that postoperative pain care is moving away from opioid-centered prescribing toward multimodal, opioid-sparing protocols, with the strongest practical signal around NSAIDs paired with dexamethasone or reg…
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