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TL;DR: A 2026 Neurological Sciences study followed 216 early Parkinson’s patients for 2 years after levodopa started and found that several non-motor symptom differences between men and women persisted or emerged despite adjustment for baseline scores and levo…
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TL;DR: A 2026 medRxiv preprint linked pre-surgery diffusion MRI markers in Parkinson’s disease to 6-month changes in impulsive-compulsive behaviour after subthalamic deep brain stimulation. Key Findings Small DBS cohort: Researchers followed 35 Parkinson’s dis…
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TL;DR: A 2026 Nature Methods paper described a self-localized ultrafast pencil beam that made volumetric multiphoton imaging faster and more stable, including 1-minute 3D scans of transferrin uptake in a live human blood-brain barrier model. Key Findings Optic…
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TL;DR: A 2026 study in Journal of Medical Case Reports described organophosphate-induced delayed neuropathy (OPIDN), a delayed nerve-injury syndrome, in a 44-year-old pesticide applicator after years of low-level exposure without a typical acute poisoning cris…
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TL;DR: A 2026 mouse study in Communications Biology found that activating parvalbumin (PV) interneurons, inhibitory nerve cells in the orbitofrontal cortex, reduced default mode network connectivity and decreased normal social approach and sniffing behavior. K…
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TL;DR: A 2026 retrospective ICU study in the International Journal of General Medicine found that 24-hour open visiting was associated with lower delirium incidence and lower anxiety/depression scores than 1-hour restricted visiting in chronic critically ill p…
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TL;DR: A 2026 study in PLOS One found that Texas ICU COVID-19 hospitalizations coded for current nicotine dependence had lower crude and adjusted mortality than hospitalizations coded as never nicotine dependent, but the administrative-data design means the re…
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TL;DR: A 2026 randomized phase 2b trial in Journal of Clinical Psychopharmacology found that the PDE10A inhibitor MK-8189 did not improve Positive and Negative Syndrome Scale (PANSS) schizophrenia symptom scores more than placebo after 6 weeks, while risperido…
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TL;DR: A 2026 study in Neuropsychopharmacology used CRISPR gene editing in human microglia-like cells and found that several schizophrenia-linked genes changed phagocytosis, cell shape, and immune-transcription programs. Key Findings Schizophrenia-linked micro…
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TL;DR: A 2026 qualitative analysis in PLOS One used 505 ME/CFS memorial entries to map how systemic neglect, clinical dismissal, social isolation, and personal burden appeared in accounts of illness and death. Key Findings 505 memorial entries: The analysis us…
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