TL;DR: A 2026 study in Microbiome found that in older adults at metabolic risk, virgin olive oil was linked to better cognitive preservation and richer gut microbiota, while common refined olive oil pointed the other way. Key Findings Metabolic-risk cohort tracked over time: The analysis followed 656 older adults who were 55-75 years old, cognitively …
TL;DR: A 2026 three-wave experimental study in Communication Research (N=3,000+ adults across the US and the Netherlands) found that AI-generated political deepfake videos damaged the reputations of targeted politicians even when viewers correctly suspected the footage was fake — and standard fact-checks restored authenticity perception without reversing the reputational harm. Key Findings Three-wave experiment, 3,000+ …
TL;DR: A 2026 study in npj Mental Health Research found that a 308-person multimodal MRI study found treatment-resistant depression carried a distinct structure-function decoupling pattern, and machine-learning models separated TRD from non-resistant depression with AUCs up to 0.95. Key Findings 72 TRD patients analyzed: The final sample included 72 patients with treatment-resistant depression, 152 with …
TL;DR: A 2026 study in PNAS found that across convention-learning experiments, people explored uncertain options at first, then committed once enough evidence crossed a Tolerance Principle threshold rather than simply copying others or optimizing probabilities. Key Findings Two-stage learning fit behavior: Participants behaved probabilistically while uncertain, then shifted into stable choices once accumulated evidence crossed …
TL;DR: A 2025 study in Nutrients found that a systematic review of adolescent diet and mental health found the clearest readout for whole dietary patterns, while single nutrients and supplement-style interventions looked less consistent. Key Findings 19 studies reviewed: The review covered six randomized controlled trials and 13 prospective cohort studies. Diet patterns looked clearer: …
TL;DR: A 2026 human microbiome and intervention study in Nature Communications found that coffee drinkers showed distinct gut microbiome composition and lower several microbial metabolites, while caffeinated and decaffeinated coffee shifted stress and mood measures in the intervention phase. Key Findings Study type: a study of habitual coffee intake, caffeinated and decaffeinated coffee, gut microbes, …
TL;DR: A 2026 study in NEJM Evidence found that solriamfetol added 9.4 minutes of objective wakefulness in early-morning shift work disorder after 4 weeks, without a higher overall adverse-event rate than placebo. Key Findings 78 early-morning workers: Participants had excessive sleepiness linked to shifts starting between 3 a.m. and 7 a.m. Randomized double-blind design: The …
TL;DR: A 2026 rat study in Neuropsychopharmacology found that chemogenetically inhibiting a prelimbic cortex to nucleus accumbens core pathway blocked cue-triggered cocaine seeking after cocaine alone, but did not block relapse-like behavior after sequential cocaine and alcohol use. Key Findings The model tested sequential polysubstance use: rats self-administered cocaine, then some received access to 20% …
TL;DR: A 2026 study in Journal of Clinical Sleep Medicine found that in 65 continuous positive airway pressure (CPAP) adherent patients with obstructive sleep apnea, those who still showed objective daytime sleepiness on a psychomotor vigilance task scored worse on global cognition, memory, executive function, attention, and processing speed despite using their devices regularly. Key …
TL;DR: A 2026 preprint in medRxiv trained machine-learning models on Danish electronic health records and found that an XGBoost model predicted clozapine initiation within 365 days with an AUROC of 0.81 in patients with schizophrenia or schizoaffective disorder. Key Findings 229,761 prediction times: The main model used routine psychiatric hospital contacts from 5,806 patients after …
