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TL;DR: In a Chinese trial of 108 breast cancer survivors, 7 weeks of daily self-acupressure eased a combined score for fatigue, poor sleep and low mood more than pressing fake points or usual care. The gains held 12 weeks later, though all results were self-re…
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TL;DR: In a small Pakistan pilot, 23 of 25 adults given an Urdu version of a talk therapy for anxiety and depression finished all 14 weeks. The trial was too small to show the therapy works. Key Findings Signed up and stayed: 51 adults were randomly assigned t…
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TL;DR: Across 55 trials in low- and middle-income countries (5,041 adults), people who got therapy had much lower PTSD symptoms than people on a wait-list or other comparison. The evidence was very low certainty because many trials were weakly run. Key Finding…
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TL;DR: In a pooled review of 8 studies of 980 people with depression and sleep problems, sleep tests showed more deep sleep and less light sleep after taking trazodone than before. Compared with placebo, though, the deep-sleep gain was not clear, and drowsines…
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TL;DR: Across 5 small trials of 343 people after stroke, people who sat in bright morning light reported better sleep quality than comparison groups. But measured time awake at night showed no clear change, so the benefit may be more about how sleep feels. Key…
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TL;DR: A therapy app did not reduce depression scores more than a look-alike education app in a trial of adults with past concussions. Insomnia scores improved more with the therapy app, but only 42 of 113 participants completed the main 12-week check-in. Key…
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TL;DR: Women who reported 10+ brain injuries from a partner performed on a speed test like someone about 21 years older than their actual age. They scored about 11 years “older” than survivors with no brain injury; the study of 207 women found a link, not proo…
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TL;DR: A 2026 pooled analysis in CNS Drugs combined two six-week trials of adults whose depression hadn’t responded well enough to an antidepressant. Adding the antipsychotic lumateperone instead of a placebo raised the share of people with side effects from 4…
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TL;DR: A 2026 meta-analysis in Neurological Sciences pooled 10 studies that gave people with Parkinson’s disease, tested while on their dopamine medication, and healthy adults the same “think of as many ideas as you can” tasks. On average, the two groups score…
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TL;DR: A meta-analysis pooling 63 studies and 265,079 people found that cannabis users had about twice the odds of committing violence as non-users (2.05 times in the general population, 2.49 times among psychiatric patients). The gap shrank to 1.17 times in s…
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