Early Psychosis Linked to Work and Education Disruption in SEEearly Cohort

Early Psychosis Linked to Work and Education Disruption in SEEearly Cohort

TL;DR: A 2026 study in European Archives of Psychiatry and Clinical Neuroscience found that more than half of 184 young adults entering an early-psychosis supported employment and education trial were not in work, school, or training, even though nearly all had finished at least lower- or upper-secondary schooling. Key Findings The SEEearly cohort included 184 …

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Blood miRNAs Linked to Hippocampal Volume and Brain Atrophy

Blood miRNAs Linked to Hippocampal Volume and Brain Atrophy

TL;DR: A 2026 Molecular Psychiatry study linked blood-derived microRNAs, short RNA regulators that help control gene expression, to left hippocampal volume and later brain atrophy in adults from the Rhineland Study. Key Findings Baseline MRI cohort: Researchers compared blood microRNA expression in 2,062 adults with baseline MRI measures of left and right hippocampal volume, hippocampal …

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Youth Cannabis Use Linked to Flatter Cognitive Development

Youth Cannabis Use Linked to Flatter Cognitive Development

TL;DR: A 2026 Neuropsychopharmacology study of 11,036 ABCD participants found youth who initiated cannabis use showed flatter cognitive-development trajectories from ages 9 to 17, with hair-detected THC linked to worse episodic-memory change. Key Findings 11,036 youth were followed: Researchers used the Adolescent Brain Cognitive Development (ABCD) Study to track neurocognitive performance from late childhood into …

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Young Men Reported More Dominance-Seeking Moral Grandstanding

Young Men Reported More Dominance-Seeking Moral Grandstanding

TL;DR: A 2026 study in Political Psychology found that men ages 18 to 35 reported the highest levels of dominance-seeking moral grandstanding, a form of moral expression aimed at putting opponents down rather than only defending a belief. Key Findings Dominance-seeking moral grandstanding was highest among men ages 18 to 35. Four-country survey: 8,420 adults …

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When Biopolymer Injections End in Delusional Infestation

When Biopolymer Injections End in Delusional Infestation

TL;DR: A 2026 study in Cureus found that a 55-year-old woman developed anxiety, somatic hypervigilance, and eventual delusional infestation after illicit cosmetic biopolymer injections, raising the possibility that chronic inflammatory exposure can help tip vulnerable patients into a secondary Ekbom syndrome. Key Findings One 55-year-old patient with no prior psychiatric history: The case centers on …

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Opioid Use Disorder Drove 30-Year Rise in US Substance Use Burden

Opioid Use Disorder Drove 30-Year Rise in US Substance Use Burden

TL;DR: A 2026 study in Population Health Metrics used Global Burden of Disease 2019 estimates and found that U.S. substance-use-disorder health loss rose sharply from 1990 to 2019, with opioid use disorders driving the largest increase. Key Findings 19.5 million cases: Estimated U.S. substance use disorder prevalence increased from 12.6 million in 1990 to 19.5 …

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Uncensored Trauma Videos Were Linked to Higher PTSD Symptoms

Uncensored Trauma Videos Were Linked to Higher PTSD Symptoms

TL;DR: A 2026 preprint cohort analysis in medRxiv found that about 24.1% of the sample met the PCL-5 threshold for probable post-traumatic stress disorder, or PTSD, while frequent uncensored video exposure was associated with higher PTSD symptom severity after accounting for other risk factors. Key Findings Indirect trauma design: Researchers studied people who were not …

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UK Perinatal Lithium Prescribing Was Rare and Often Interrupted

UK Perinatal Lithium Prescribing Was Rare and Often Interrupted

TL;DR: A 2026 cohort study in The British Journal of Psychiatry found that lithium prescribing around pregnancy was rare in UK primary care records, and most pre-pregnancy lithium users did not stay on treatment through all three trimesters. Key Findings 752,112 pregnancies analyzed: Researchers used UK Clinical Practice Research Datalink GOLD records from 1995 to …

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Depressive Symptoms Accelerated Four Years Before Death in Twin Consortium

Depressive Symptoms Accelerated Four Years Before Death in Twin Consortium

TL;DR: A 2025 study in Psychological Science found that depressive symptoms accelerated about 4 years before death in a multinational twin consortium, suggesting that late-life mood worsening can partly reflect terminal decline rather than chronological age alone. Key Findings 2,411 older-adult records: Researchers analyzed longitudinal depressive-symptom data from the Interplay of Genes and Environments across …

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Rotenone Parkinson’s Fly Model Showed Sex-Specific Gene Responses

Rotenone Parkinson's Fly Model Showed Sex-Specific Gene Responses

TL;DR: A 2026 fly study in IBRO Neuroscience Reports found that long-term rotenone exposure produced stronger survival, climbing, oxidative-stress, and late immune-gene disruption in male Drosophila than in female flies. Key Findings 90 flies per sex were tracked: Survival assays used three sets of 30 male or female flies after rotenone feeding. Two disease windows …

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