TL;DR: A 2026 narrative review in International Journal of General Medicine argued that apathy in Alzheimer’s disease is tied to damage across motivation circuits, including the anterior cingulate cortex, orbitofrontal cortex, striatum, locus coeruleus, and large-scale brain networks. Key Findings Apathy was framed as its own syndrome: The review separates reduced goal-directed behavior from depression, …
TL;DR: A 2026 study in eLife found that infants’ brains responded more strongly to structured children’s music than shuffled music by 3 months, while clearer music-linked movement patterns appeared mainly by 12 months. Key Findings 79 infants tested: Researchers recorded electroencephalography (EEG), a scalp measure of brain electrical activity, and video-based body movement in 3 …
TL;DR: A 2026 mouse study in Nature Communications found that deleting ankyrin-2 (Ank2) from hippocampal astrocytes left recent memory intact but weakened remote memory, pointing to astrocyte structure as part of how memories stay stable over time. Key Findings Recent recall stayed intact: Mice lacking astrocytic Ank2 performed normally in the day-1 contextual fear memory …
TL;DR: A 2026 preprint in medRxiv found that stroke survivors doing motor imagery showed changing brain-heart coupling across rehabilitation sessions, especially between cardiac sympathetic activity and electroencephalography (EEG) beta-band network clustering. Key Findings 15 stroke survivors: Researchers analyzed two cohorts with upper- or lower-limb motor impairment after stroke. 2 motor-imagery protocols: Dataset 1 used gait …
TL;DR: A 2026 preprint posted on medRxiv reported that resting-state electroencephalography (EEG) neural slowing after stroke tracked secondary thalamic degeneration measured on structural MRI, even though the sampled patients did not have direct thalamic lesions. Key Findings 25 stroke patients: Researchers studied adults at least 3 months after unilateral supratentorial stroke and compared their resting-state …
TL;DR: A 2026 review in International Journal of Molecular Medicine mapped how exercise and fluoxetine overlap in Alzheimer’s disease mechanisms such as mitochondrial quality control, oxidative stress, inflammation, and neuroplasticity, but clinical combination benefits remain unproven. Key Findings Review article, not trial: Wu and Li synthesized mechanistic evidence on exercise and fluoxetine in Alzheimer’s disease …
TL;DR: A 2026 preprint posted on medRxiv reported that larger choroid plexus volume on brain MRI was associated with greater disability in multiple sclerosis and with higher white-matter myo-inositol in progressive MS, but the work has not yet been peer reviewed. Key Findings 88-person imaging sample: Researchers studied 45 people with multiple sclerosis and 43 …
TL;DR: A 2026 case study in International Medical Case Reports Journal described a 42-year-old man whose chronic insomnia improved after celiac disease was diagnosed and treated with a gluten-free diet, but the report cannot prove gluten exposure caused the sleep problem. Key Findings 5 months of insomnia: The patient reported persistent difficulty initiating and maintaining …
TL;DR: A 2026 systematic review and meta-analysis in Brain, Behavior, & Immunity – Health found that adding celecoxib to antidepressants was linked to lower depressive symptom scores in 7 small trials, but the efficacy evidence was rated very low certainty. Key Findings 7 randomized trials: The meta-analysis included 365 adults with major depressive disorder, with …
TL;DR: A 2026 systematic review and meta-analysis in Journal of Alzheimer’s Disease found that choroid plexus volume, an MRI-visible structure involved in cerebrospinal-fluid regulation and immune signaling, was larger in Alzheimer’s disease than in healthy controls. Key Findings Sixteen studies: The review included 16 MRI-based studies covering 2,004 Alzheimer’s disease patients and 883 healthy controls. …
