Web Pregnancy Program Did Not Beat Control for Substance Use or STI Risk

Web Pregnancy Program Did Not Beat Control for Substance Use or STI Risk

TL;DR: A 2026 randomized trial in Journal of Medical Internet Research tested the web-based Health Check-Up for Expectant Moms program in 176 pregnant women at risk for substance use or sexually transmitted infection risk, but reductions in alcohol, cannabis, and condomless sex did not differ clearly from an attention-matched control condition. Key Findings 176 pregnant …

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Fisetin Plus Training Improved Maresin-1 and HOMA-IR in Obesity Trial

Fisetin Plus Training Improved Maresin-1 and HOMA-IR in Obesity Trial

TL;DR: A 2026 randomized trial in Journal of the International Society of Sports Nutrition found that 12 weeks of combined interval resistance and aerobic training increased Maresin-1, an inflammation-resolving lipid mediator, in men with obesity, with the largest insulin-resistance improvement when training was paired with 200 mg/day fisetin. Key Findings 44 men completed the trial: …

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CBT Online Self-Help Group Reduced Depression Symptoms in RCT

CBT Online Self-Help Group Reduced Depression Symptoms in RCT

TL;DR: A 2026 randomized trial in JMIR mHealth and uHealth found that a 7-session CBT-based online self-help group reduced depression symptoms, with the average Beck Depression Inventory-II score moving from the moderate range to the mild range after the program. Key Findings Depression scores decreased: The CBT-based online self-help group fell from a mean BDI-II …

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Exercise Before CBT Linked to Higher Depression Remission in Pilot Trial

Exercise Before CBT Linked to Higher Depression Remission in Pilot Trial

TL;DR: A 2026 randomized pilot trial in the Journal of Affective Disorders found that 30 minutes of moderate exercise before cognitive behavioral therapy (CBT) for major depressive disorder was linked to stronger therapy-process measures and higher exploratory remission than quiet rest before CBT. Key Findings Forty adults with major depressive disorder were randomized: Nineteen received …

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Lithium Loading Dose Plus Quetiapine Reduced Acute Mania More Than Standard Titration

Lithium Loading Dose Plus Quetiapine Reduced Acute Mania More Than Standard Titration

TL;DR: A 2026 randomized single-blind trial in BMC Psychiatry found that a one-day lithium carbonate loading dose plus quetiapine reduced acute manic symptoms in bipolar I disorder more than standard slow-titration lithium plus quetiapine over 14 days. Key Findings 60 inpatients randomized: Adults with bipolar I disorder in acute mania, all meeting DSM-5 criteria and …

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CBT-I Self-Help Book Reduced Daily Hypnotic Use in GP Insomnia Patients

CBT-I Self-Help Book Reduced Daily Hypnotic Use in GP Insomnia Patients

TL;DR: A 2025 randomized trial in Scandinavian Journal of Primary Health Care found that a self-help book based on cognitive behavioral therapy for insomnia (CBT-I), a structured non-drug insomnia treatment, reduced daily hypnotic sleep-medication use and anxiety screening rates more than a brief sleep-hygiene handout among Norwegian general-practice patients prescribed zopiclone or zolpidem. Key Findings …

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Mobile Neurofeedback for ADHD in Children: Adjunct Treatment Option?

Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders affecting children. A new randomized controlled trial published in the Journal of Korean Medical Science suggests that mobile neurofeedback training may help improve attention and reduce symptoms in children with ADHD. Key Takeaways: 74 children aged 8-15 with ADHD participated in a …

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