TL;DR: A 2026 medRxiv preprint found that adults with multiple sclerosis showed accelerated long-term forgetting (ALF), meaning unusually steep memory loss over days despite normal early recall, on two verbal memory tests. Key Findings The long-delay test was the key contrast: researchers compared 62 adults with multiple sclerosis and 65 matched controls using word-list and …
TL;DR: A 2026 study in Alzheimer’s & Dementia: Translational Research & Clinical Interventions used lecanemab pharmacokinetic/pharmacodynamic modeling in early Alzheimer’s disease and found that blood biomarkers worsened after treatment stopped, while monthly maintenance dosing after 18 months was predicted to preserve most p-tau181 and GFAP, an astrocyte-inflammation protein. Key Findings Three plasma biomarkers improved: Lecanemab …
TL;DR: A 2026 study in Cognitive, Affective, & Behavioral Neuroscience used task-based functional MRI (fMRI), a brain-scan method that tracks blood-oxygen changes during a task, to show that misophonia and hyperacusis had partly different brain connectivity patterns during unpleasant sound processing. Key Findings 91 young adults were analyzed after 1 participant was excluded for excessive …
TL;DR: A 2026 medRxiv preprint enrolled 177 adults with migraine in a 30-day smartphone study and found that daily cognition and symptom check-ins were feasible, with 3,688 completed assessments and higher baseline burden in chronic migraine. Key Findings Migraine cohort: The MIND study followed 177 adults with migraine using once-daily smartphone surveys and brief mobile …
TL;DR: A 2026 preprint posted to medRxiv found that adults with migraine had worse brain fog, more task forgetting, and slower smartphone cognitive-test performance on headache days, suggesting that migraine-related cognitive symptoms can be measured in daily life rather than only in clinic visits. Key Findings Brain fog affected 60% of headache days: participants contributed …
TL;DR: A 2026 Nature Communications study found that extra MeCP2, the dosage-sensitive protein linked to Rett syndrome and MECP2 duplication syndrome, disrupted neural progenitor cells far more than mature neurons by activating developmental genes too early. Key Findings Cell timing mattered: MeCP2 overexpression caused broad transcriptional changes in neural progenitor cells, but only modest changes …
TL;DR: A 2026 Critical Care Explorations paper described a 17-year-old girl whose intentional lisdexamfetamine overdose was followed by delayed severe heart failure, with left ventricular ejection fraction falling below 20% before recovery over months. Key Findings Delayed cardiac collapse: The patient first appeared stable after treatment, then worsened again about 24 hours after ingestion. Severe …
TL;DR: A 2026 systematic review and meta-analysis in Neurological Sciences found that ketogenic diet (KD), a very-low-carbohydrate diet designed to raise ketone fuel use, looked feasible and generally safe as an add-on strategy in glioblastoma (GBM), but the survival signal still needs phase III randomized proof. Key Findings The review included 41 human studies of …
TL;DR: A 2025 study in The Journal of General Psychology found that introductory psychology textbooks showed modest improvement from 2018 to 2023, but several classic myths and contested topics were still presented in biased or oversimplified ways. Key Findings Researchers rated coverage of 11 textbook topics that psychology professors had flagged as commonly distorted or …
TL;DR: A 2026 study in Genes & Diseases found that Il6 deficiency, meaning loss of the gene for interleukin-6, worsened Parkinson’s-like motor and dopamine-system injury in mice. Key Findings Il6 knockout worsened movement: Mice lacking Il6 performed worse after MPTP, a toxin commonly used to model Parkinson’s-like dopamine injury. Female knockout mice showed earlier damage: …
