
TL;DR: A 2026 study in Biological Psychiatry: Global Open Science found that trauma-exposed adolescents, especially those with higher posttraumatic stress symptoms, showed disrupted parent-cued fear extinction across skin-conductance, behavioral-learning, and…
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TL;DR: A 2026 medRxiv preprint from the ENIGMA Addiction Working Group used structural MRI from 2,782 people with substance use disorder (SUD) and 1,951 controls and reported that addiction-related brain differences followed cortical network hubs and neurotran…
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TL;DR: A 2026 systematic review and meta-analysis posted as a medRxiv preprint found that mindfulness-based programs were linked to a small improvement in executive function, meaning inhibition, working memory, and flexible thinking, across 13 youth trials. Ke…
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TL;DR: A 2026 study in Psychological Medicine found that people with schizophrenia spectrum disorders and higher avolition or moderate-to-high delusion severity appeared to improve more after virtual reality cognitive behavioral therapy for psychosis (VR-CBTp)…
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TL;DR: A 2026 preprint on medRxiv tested transcutaneous vagus nerve stimulation (tVNS), a noninvasive ear-based stimulation method, during a grip-strength reward task and found that people with severe depressive symptoms made more efficient effort choices unde…
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TL;DR: A 2026 machine-learning study in PLOS One used student mental-health survey features to test an interpretable FT-Transformer plus LSTM model, which reached 95% accuracy for low, medium, and high risk prediction in a public dataset. Key Findings 95% accu…
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TL;DR: A 2026 review in Neuroscience & Biobehavioral Reviews found that chronic primary pain studies most consistently linked higher pain sensitivity with lower mean arterial pressure, higher cortisol, higher heart rate during recovery, and lower parasympathet…
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TL;DR: A 2026 medRxiv preprint found that soluble CD27 (sCD27), a T-cell activation marker, was elevated in a subgroup of patients with severe psychiatric disorders and was more common when autoimmune disease or abnormal cerebrospinal fluid (CSF) inflammation…
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TL;DR: A 2026 rat study in Neuropsychopharmacology reported that repeated semaglutide treatment reduced cocaine-vs-food choice in male and female rats, supporting further clinical testing for cocaine use disorder rather than proving human benefit. Key Findings…
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TL;DR: A 2026 study in BMC Psychiatry used Taiwan insurance records to find that dementia in people with schizophrenia was tied more strongly to age and linked medical comorbidities than to antipsychotic exposure after multivariable adjustment. Key Findings 14…
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